On Wall Street, the Dow Jones Industrial Average fell 69.85 points, or 0.27%, to 26,087.31. The S&P 500 lost 4.74 points, or 0.16%, to 2,883.47 and the Nasdaq Composite dropped 27.24 points, or 0.34%, to 7,937.00.
In currency trading, the dollar index rose 0.25%, with the euro down 0.16% to $1.1255.
The Japanese yen weakened 0.59% versus the greenback at 111.68 per dollar. Sterling fell 0.29% to $1.3051, suggesting fears remain about Brexit.
Germany's 10-year bond yield edged up toward 0.0% after the Brexit announcement, while a signal from the European Central Bank that it will fight low economic growth and inflation boosted peripheral debt.
Germany's 10-year bond yield was up 0.02 percentage point at negative 0.01%.
U.S. Treasury benchmark 10-year notes last fell 6/32 in price to yield 2.5006%.
Oil prices fell more than 1% after sources said that the Organization of the Petroleum Exporting Countries may raise output from July if Venezuelan and Iranian supplies fall further and prices keep rallying.
U.S. crude fell $1.03 to settle at $63.58 per barrel. Brent settled down 90 cents at $70.83. Gold prices fell more than 1%, slipping below the key $1,300 level, as robust economic data from the United States boosted the dollar, taking the sheen off the safe-haven metal.
U.S. gold futures settled 1.6% lower at $1,293.3 an ounce.
Source: Saudi Press Agency